CDPH Warns Retailers and Public About the Dangers of Kratom-derived Products and 7-OH

The agency wants 7-OH classified as Schedule I, a category reserved for illicit drugs with no medical use and a high potential for abuse — alongside heroin and LSD. There are no approved drugs containing it, and no legal basis for companies to claim it helps with pain or anxiety, according to the agency. That’s because kratom’s active ingredients — mitragynine and 7-hydroxymitragynine (7-OH) — bind to the same brain receptors as morphine and alcohol, triggering a rush of dopamine, the body’s “feel good hormone.” Real Botanicals remains committed to providing safe, lab-tested, naturally extracted 7-OH products in compliance with state and federal law. These types of products are here to stay, but we must ensure we continue to access them legally as the situation evolves.

Kratom Capsules

Susan Ash, the founder of the AKA, used kratom as a substitute for Suboxone, a medication used to treat OUD. Kratom comes from the leaves of a tropical tree that grows in Southeast Asia, where it has been used for centuries as a natural stimulant and pain reliever. Although the main purpose of the placebo-controlled trial is to test the safety and tolerability of mitragynine – not whether it can treat OUD – the fact that NIH is even conducting such a study is being hailed as a “major milestone” by kratom advocates. Hopefully this work will lead to a new treatment option for people with opioid use disorder and support a path to recovery,” Joni Rutter, PhD, Director of the NIH’s National Center for Advancing Translational Sciences, said in a press release. “We’ve seen the potential of mitragynine in the lab, and now we’re finally able to examine its potential in people.

What Is This Kratom Stuff? Read Our Blog Before You Purchase Kratom

Stick with transparent vendors that sell natural-leaf powder and capsules, publish lab testing, verify age (21+), and label products clearly. This is the kratom news headline most natural-leaf retailers were watching this week. The flagged products included tablets, gummies, drink mixes, and shots — formats the agency says are sometimes disguised or marketed as ordinary kratom even though they deliver a far more potent, concentrated compound. Kratom supporters say, in its natural form, the plant can help curb opioid addiction and manage pain. NASHVILLE, Tenn. (WZTV) — Tennessee lawmakers have passed a full ban on kratom, derived from a Southeast Asian plant, following a weeks-long debate over its safety and effects. Reports of death have been linked to kratom products as well in combination with other substances.

Is Kratom safe to use daily?

There are no FDA-approved 7-OH drugs, according to the health agency. "7-OH is an opioid that can be more potent than morphine. We need regulation and public education to prevent another wave of the opioid epidemic." FDA Commissioner Marty Makary, M.D., M.P.H., wrote in a statement that vape stores are "popping up in every neighborhood in America, and many are selling addictive products like concentrated 7-OH." In a Tuesday press release, the HHS announced that the FDA is recommending a scheduling action to control these products under the Controlled Substances Act (CSA).

Red Vein Kali Kratom Powder

Kratom leaf companies have tried to distinguish themselves as wholly different from 7-OH manufacturers, who disagree with such delineations. The same allure pushed it into gyms, weight rooms and combat sports, where athletes look for ways to increase endurance and ease painful injuries. At the time of his arrest in April, Clarke had a THC vape pen on him and a prescription for a painkiller often used for sports injuries, according to the dashcam audio. “Because the partnership carried the league’s endorsement, some players understandably viewed that as a signal that the product had been appropriately vetted,” Jacobs said. “Not only that, it’s going to last you six to eight hours just depending on your body type and your genetic makeup,” she added.

• We do not offer free shipping on all products at this time, only on special free shipping sale days.
• The use of kratom in any form has not been approved by the FDA but the agency is particularly scrutinizing 7-OH.
• More recently, bills were introduced this 2025–26 legislative session in states like Delaware, Illinois, Michigan, South Dakota, and Tennessee that would prohibit kratom and kratom products within their boundaries.
• While GLP-1 medications like Ozempic and Wegovy hold promise for both weight loss and diabetes management, their potential for accidental misuse requires caution.
• The biggest national kratom news this week came from the U.S.
• If you prefer not to have your kratom flavored they offer that too with the Classic.

Appreciating this distinction is critical to understanding the legal landscape. The short answer is that it depends on VR Kratom where you live and what type of product you're buying. Only mitragynine, 7-hydroxymitragynine, speciociliatine, and corynantheidine are currently known to be pharmacologically active.

A lesser known therapeutic use of kratom is to reduce cravings for opioids and other substances. These schedules mimic the federal controlled substances schedule that was created by the Controlled Substances Act of 1970, where substances are scheduled depending on their medical usefulness and potential for addiction or abuse. A variation on a ban is the decision to add kratom or one of its primary compounds, 7-OH, to a state’s controlled substances schedule. More recently, bills were introduced this 2025–26 legislative session in states like Delaware, Illinois, Michigan, South Dakota, and Tennessee that would prohibit kratom and kratom products within their boundaries. It is worth noting that states have generally considered several bills related to kratom in a single legislative session that offer different approaches to address the rising use of kratom and kratom-related products.